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桥本甲状腺炎甲状腺细针穿刺两种细胞学亚型临床特点比较
引用本文:刘丽,高燕明,卢桂芝,袁振芳,高莹,惠岩,郭晓蕙,唐素恩,高妍. 桥本甲状腺炎甲状腺细针穿刺两种细胞学亚型临床特点比较[J]. 中华内分泌代谢杂志, 2010, 26(4). DOI: 10.3760/cma.j.issn.1000-6699.2010.04.005
作者姓名:刘丽  高燕明  卢桂芝  袁振芳  高莹  惠岩  郭晓蕙  唐素恩  高妍
作者单位:大学第一医院内分泌科,北京,100034
摘    要:回顾性分析397例经甲状腺细针穿刺细胞学(FNAC)确诊桥本甲状腺炎患者的临床特点.发现嗜酸细胞型(n=181)及淋巴细胞型(n=186)桥本甲状腺炎临床表现、抗甲状腺自身抗体(甲状腺球蛋白抗体、甲状腺过氧化物酶抗体)水平无差异.嗜酸细胞型较淋巴细胞型更倾向进展为甲状腺功能减退,可能为疾病进程中晚期阶段.

关 键 词:桥本甲状腺炎  甲状腺  细针穿刺细胞学  亚型

Patients with Hashimoto's thyroiditis confirmed by fine-needle aspiration cytology:comparison of clinical features of two subtypes
Abstract:Three hundred and ninety-seven patients of Hashimoto's thyroiditis(HT)confirmed by fine-needle aspiration cytology(FNAC)were investigated retrospectively.Between oxyphil cell subtype(OC,n=181)and lymphocytic cell subtype(LC,n=186),there were no significant differences in clinical manifestation and levels of thyroglobulin antibody(TgAb)and thyroid peroxidase antibody(TPOAb).However,compared with lymphocytic cell subtype,the patients with oxyphil cell subtype had the tendency to develop hypothyroidism,suggesting advanced stage of Hashimoto's thyroiditis.
Keywords:Hashimoto's thyroiditis  Thyroid gland  Fine-needle aspiration cytology  Subtypes
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