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枸杞在糖尿病大鼠视网膜组织抗氧化反应中的作用
引用本文:何剑峰,仇宜解.枸杞在糖尿病大鼠视网膜组织抗氧化反应中的作用[J].中国中医眼科杂志,1997,7(3):131-134.
作者姓名:何剑峰  仇宜解
作者单位:柳州市第一人民医院眼科,青岛医学院附属医院眼科,连云港市第一人民医院眼科
摘    要:探讨枸杞在糖尿病大鼠视网膜组织抗氧化反应中的作用。方法:36只Wistar大鼠随机分为Ⅰ,Ⅱ,Ⅲ组,其中Ⅱ,Ⅲ组大鼠用链脲佐菌素诱发糖尿病,然后观察枸杞对糖尿病大鼠视网膜组织中剩余抗坏血酸水平,超氧化物歧化酶活性及脂质过氧化物歧化酶含量的短期效应。

关 键 词:糖尿病  实验性  视网膜  枸杞

A research of the effect of lycium barbarum L. to antioxidizing reaction in the retinal tissue of diabetic rats
He Jianfeng ,Qiu Yigie ,Bao Lianyun ,et al.A research of the effect of lycium barbarum L. to antioxidizing reaction in the retinal tissue of diabetic rats[J].Journal of Traditional Chinese Ophthalmology,1997,7(3):131-134.
Authors:He Jianfeng  Qiu Yigie  Bao Lianyun  
Institution:He Jianfeng 1,Qiu Yigie 2,Bao Lianyun 3,et al 1 Department of Ophthalmology,Liouzhao First People Hospital,Guangxi 545001
Abstract:OBJECTIVE: To study the effect of lycium barbarum L. in antioxidizing reaction in the retinal tissure of diabetic rats. METHODS: 36 wistar rats were divided into I,II,III groups by random, the rats in II, III groups were induced diabetes by streptozotocin, the short-term effects of lycium barbarum L. on the levels of residual ascorbete (RA), the activities of superoxide dismutase (SOD), and the quantities of lipid peroxide (LPO) in retinal tissue of diabetic rats were investigated. RESULTS: In the retinal tissue of diabetic rats, the levels of RA and the activities of SOD were evidently decreased, the quantities of LPO was obviously increased. But, in treated group of lycium barbarum L., RA and SOD were not evidently decreased, LPO was not obviously increased. The difference was sigificance compared with the untreated group of diabetic rats (P<0.05). CONCLUSION: Lycium barbarum L could protect retinal tissue of diabetic rats from oxidizing injury.
Keywords:experimental diabetes    retina  lycium barbarum L  
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