Concurrent development of Crohn disease and myelodysplastic syndrome in a child: case report and literature review |
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Authors: | Nahas Sergio Carlos Nahas Caio Sergio Rizkallah Marques Carlos Frederico Borba Marcelo Rodrigues Helito Alfredo Salim Odoni Vicente |
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Affiliation: | Department of Gastroenterology-Digestive Surgery Division, Hospital das Clínicas, Medical School, University of S?o Paulo, S?o Paulo, Brazil. caionahas@uol.com.br |
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Abstract: | A small number of cases of Crohn disease associated with myelodysplastic syndromes or leukemia have been reported in adults in the last 25 years in the English-language medical literature. The authors report a case of a 9-year-old boy who developed Crohn disease and myelodysplastic syndrome concurrently. Analysis of his bone marrow showed a chromosome 20 abnormality. Although chromosome 20 abnormalities have been reported in a minority of these patients, the significance of this association remains unclear at the present time. |
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