三种常见革兰阴性菌医院感染的耐药性分析

目的　了解大肠埃希菌、铜绿假单胞菌及克雷伯菌属医院感染的耐药情况。方法　对来源于全省医院感染监控网医院710株细菌的耐药性进行统计分析。结果　 3种细菌对氨苄西林的耐药率均 >90 %。大肠埃希菌和铜绿假单菌对阿米卡星较敏感 ,与庆大霉素的耐药性相比差异有显著性 (P <0 0 5 ) ,铜绿假单胞菌对亚胺培南的耐药率为 32 2 6 % ,对头孢噻肟为89 19%。结论　 3种常见革兰阴性菌对多数抗生素都有较高的耐药率 ,应加强细菌耐药性监测工作 ,指导临床合理用药

Drug resistance of three common gram-negative bacteria in nosocomial infection analyse

AIM To investigate the drug resistance of Escherichia coli, Pseudomonas aeruginosa, Klebsiella in nosocomial infection. METHODS To collect date of the 710 strains of bacteria separated from nosocomial infection cases, and make analyses on the drug resistance rate of the 3 common gram negative bacteria. RESULTS The rates of ampicillin resistant Escherichia coli, Pseudomonas aeruginosa, Klebsiella were over 90%. Escherichia coli and Pseudomonas aeruginosa to amikacin showed susceptivity, as compare with gentamicin, the difference between them were significant( P <0 05). The rate of imipenem resistant Pseudomonas aeruginosa was 32 26%, and to cefotaxime was 89 19%. CONCLUSIONS The three common species were higher drug resistance for most common antibiotics strengthened the supervision towards bacterium Gram negative and reasonable advice should be given.