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| 痛经舒口服液对模型小鼠血清及组织中GSH-PX和NO的影响 | |
| 引用本文： | 吴宜艳,苏云明,邹辉,才玉婷,梁亿红,冯勤喜,于春艳,杨风华. 痛经舒口服液对模型小鼠血清及组织中GSH-PX和NO的影响[J]. 中医药学报, 2007, 35(4): 26-27 |
| 作者姓名： | 吴宜艳 苏云明 邹辉 才玉婷 梁亿红 冯勤喜 于春艳 杨风华 |
| 作者单位： | 1. 黑龙江中医药大学,黑龙江,哈尔滨,150040;牡丹江医学院,黑龙江,牡丹江,157011 2. 黑龙江中医药大学,黑龙江,哈尔滨,150040 3. 牡丹江医学院,黑龙江,牡丹江,157011 |
| 基金项目： | 黑龙江省教育厅骨干教师基金 |
| 摘 要： | 目的:探讨痛经舒口服液对小鼠原发性痛经的保护作用。方法:利用缩宫素制备小鼠痛经模型,以谷胱甘肽过氧化物酶(GSH-PX)及一氧化氮(NO)为指标观察各组药物对小鼠血清及组织的影响。结果:痛经舒口服液能升高原发性痛经小鼠血清中的谷胱甘肽过氧化物酶及一氧化氮含量(P<0.05),能升高组织中的一氧化氮含量(P<0.05)。结论:痛经舒口服液通过增加小鼠血清中谷胱甘肽氧化物酶及一氧化氮含量,及增加组织中一氧化氮的含量,进而缓解痛经,对小鼠原发性痛经有保护作用。 |
| 关 键 词： | 痛经舒口服液 谷胱甘肽过氧化物酶 一氧化氮 |
| 文章编号： | 1002-2392（2007）04-0026-02 |
| 修稿时间： | 2007-04-16 |
Influence of Tongjingshu Oral Liquid upon GSH-PX and NO in serum and tissues of experimental animals |
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| WU Yi-yan,SU Yun-ming,ZOU Hui,CAI Yu-ting,LIANG Yi-hong,FENG Qin-xi,YU Chun-yan,YANG Feng-hua. Influence of Tongjingshu Oral Liquid upon GSH-PX and NO in serum and tissues of experimental animals[J]. Acta Chinese Medicine and Pharmacology, 2007, 35(4): 26-27 | |
| Authors: | WU Yi-yan SU Yun-ming ZOU Hui CAI Yu-ting LIANG Yi-hong FENG Qin-xi YU Chun-yan YANG Feng-hua |
| Abstract: | Objective:To investigate the protective effect of Tongjingshu Oral Liquid on primary menalgia of mice.Method:The menorrhalgia model of mouse was made with oxytocin.The serum levels of GSHPX and NO were measured to prove the curative effect of Tongjingshu Oral Liquid on the serum and tissues of mice.Result:Tongjingshu Oral Liquid obviously increased the level of GSH-PX and NO in mouse serum with primary menorrheal(P<0.05),and the NO level in mouse tissues(P<0.05).Conclusion:Tongjingshu Oral Liquid has protective action on primary menorrheal of mice by increasing the levels of GSH-PX and NO in mouse serum,and the NO level in mouse tissues. |
| Keywords: | Tongjingshu Oral Liquid GSH-PX NO |
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