儿童脑神经母细胞瘤的CT、MRI和病理分析

目的 :探讨儿童脑神经母细胞瘤的CT、MRI表现及和病理的关系。方法 :对 9例经组织病理学证实的脑神经母细胞瘤进行回顾性分析 ,研究肿瘤的CT及MRI影像学特征。结果 :9例神经母细胞瘤中 ,4例肿瘤位于右侧额叶 ,1例位于左侧额叶 ,3例位于右侧颞叶并累及同侧额叶 ,1例位于左侧顶叶。 9例肿瘤均呈囊实性肿块 ,边界清楚 ,5例有钙化。肿瘤实质性部分CT平扫呈略高密度 ,MRT1WI呈等或稍低信号 ,T2 WI呈等或稍高信号 ,增强后肿瘤实性部分和囊性部分的壁明显强化。结论 :神经母细胞瘤是儿童期少见的恶性肿瘤 ,常发生钙化、囊变、坏死。肿瘤实性部分CT平扫密度通常高于脑灰质 ,MRT1WI呈等或稍低信号 ,T2 WI呈等或稍高信号。

CT, MRI and Pathological Analysis of Neuroblastomas in Children

Objective:To explore CT and MR imaging characteristics of neuroblastoms in children and correlated with pathology.Methods:Nine patients with neuroblastomas confirmed by pathology were performed CT and MR examinations.The site,morphology,CT and MR imaging features of the lesions were analyzed retrospectively.Results:Of all 9 tumors,4 were in the right frontal lobes,1 in the left frontal lobe,3 in the right temporal lobes involving the ipsilateral frontal lobes and 1 in the left parietal lobe.All the tumors were cystic and solid tissues and well-defined.Calcification was seen in 5 cases on CT images.Solid components of all tumors showed high density on CT scan and iso- or hypointensity on T 1-weighted MR images and iso- or slightly hyperintensity on T 2-weighted images.Cystic components of the tumors showed low density on CT and low signals on T 1-weighted images and high signals on T 2-weighted images.The solid portions of the tumors strikingly enhanced with contrast materials.Conclusion:Neuroblastomas are less common malignant tumors in children.Calcification,cystic change,necrosis and high density of the solid parts of the tumors on CT scan and iso- or hypointensity on T 1WI and iso- or slightly high signals on T 2WI are characteristics of the tumors.