复方阿嗪米特联合伊托必利治疗慢性心功能不全所致的消化不良

 目的 观察复方阿嗪米特联合伊托必利治疗慢性心功能不全所致的消化不良的临床疗效。方法 入选78例患者随机分为两组。对照组：口服多潘立酮片，每次10 mg，3次/d。治疗组：口服复方阿嗪米特肠溶片，每次2片，3次/d；盐酸伊托必利片，3次/d，每次50 mg。两组疗程均为2周，并在治疗1周及2周时对腹胀、餐后不适、食欲不振进行症状评分。结果 两组在治疗1周及2周时，患者的腹胀、餐后不适、食欲不振等症状评分及症状总积分均明显改善，但治疗组的下降幅度明显高于对照组（ P ＜0.05）。另外，治疗组在疗效及起效时间上也优于对照组（ P ＜0.05）。结论 复方阿嗪米特联合伊托必利治疗慢性心功能不全所致的消化不良临床疗效显著，具有起效时间短、高改善率、不良反应少的特点，对提高患者生活质量起了积极的作用。

Efficacy of compound azintamide combined with itopride in treatment of chronic cardiac insufficiency patients with dyspepsia

Objective To investigate the efficacy of compound azintamide combined with itopride in the treatment of chronic cardiac insufficiency patients with dyspepsia.Methods Seventy-eight patients with chronic cardiac insufficiency and dyspepsia were randomly divided into two groups: treatment group(42 patients) and control group(36 patients).In control group,the patients were given 10 mg domperidone tablets three times daily while the patients in the treatment group took 2 compound azintamide enteric-coated tablets and 50 mg itopride tablets three times daily for two weeks.After one week or two weeks of treatment,the index scores of abdominal distension,indisposition after meals and poor appetite were evaluated.Results Symptom scores and total symptom scores of patients in both groups were improved,especially in the treatment group(P<0.05).Moreover,the therapeutic effect and remission time in the treatment group were superior(P<0.05).Conclusions The curative effect of compound azintamide combined with itopride in the treatment of chronic cardiac insufficiency patients with dyspepsia is significant,characterized by the rapid onset,remarkable improvement and few adverse reactions.