Solubility prediction of solutes in aqueous mixtures of ethylene glycols |
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| Authors: | Jouyban A Soltanpour S Tamizi E |
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| Institution: | Faculty of Pharmacy and Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. ajouyban@hotmail.com |
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| Abstract: | The applicability of a trained version of the Jouyban-Acree model, for predicting the solubility of solutes in aqueous mixtures of ethylene glycol and its polymerized forms was shown. The solubilities of 8 drugs in binary mixtures were determined and the mean percentage deviation (MPD) was calculated as a prediction accuracy criterion and the overall MPD (+/- SD) was 23.2 (+/- 13.1)%. |
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