超声造影增强形式对乳腺病变的诊断价值

目的 探讨超声造影在乳腺病变中的应用价值.方法 对行乳腺手术的104例患者共104个病灶进行超声造影,将其增强形式分为无增强、周边增强、均匀增强、区域增强和不均匀增强.总结乳腺良、恶性病变的微血管显像特征.结果 超声造影无增强提示良性,诊断敏感性18.3%,特异性97.7%,阳性预测值91.7%,阴性预测值46.2%,准确性51.5%.周边增强提示恶性,诊断敏感性39.5%,特异性98.3%,阳性预测值94.4%,阴性预测值69.4%,准确性73.8%.结论 超声造影增强形式有助于乳腺病变的鉴别诊断.

Usefulness of contrast enhanced ultrasound in the diagnosis of breast lesions

Objective To evaluate the usefulness of contrast enhanced ultrasound in the diagnosis of breast lesions. Methods Contrast enhanced ultrasound was performed after administration of SonoVue in 104 patients scheduled for surgical tumor removal. The enhancement morphology was classified as non, peripheral,homogeneous,regional,or heterogeneous enhancement based on distribution of enhancing areas. All breast lesions enhancement morphology were analyzed, and the diagnostic value of contrast enhanced ultrasound was calculated. Results The prevalence of non enhancement was significantly higher in benign lesions than in malignant ones(P = 0.013),and the prevalence of peripheral enhancement was significantly higher in malignant lesions than in benign ones (P = 6.02 × 10-7). Conclusions Contrast enhanced ultrasound is useful in diagnosis of breast lesions.