系统性毛细血管渗漏综合征的临床研究进展

系统性毛细血管渗漏综合征为一组反复发作的低容量性低血压、血液浓缩、非蛋白尿性低蛋白血症 ,全身水肿、多数情况下伴有异型球蛋白血症的临床综合征。其原因由于毛细血管通透性增加 ,目前具体发病机理尚不明确。近年发现特布他林和茶碱对预防发作有效。临床医生应对该病提高警惕性。

Progress on Clinical Study on Systemic Capillary Leak Syndrome

Systemic capillary leak syndrome is characterized as a clinical syndrome with recurrent crises of hypovolemic hypotentension,hemoconcen tration,hypoalbuminemia without albuminuria,generalized edema,and accompanied by paraproteinemia in most cases.The clinical signs result from massive extravasat ion of plasma from intravascular into the extravascular space as a result of a s udden reversible increase in capillary permeability.The pathogenesis of SCLS is unknown.Resent reports suggest that the regimen of terbutaline and theophylline be an effective prophylaxis against SCLS.Thus clinical awareness of the syndrome need increasing.