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Multiple system atrophy masking multiple sclerosis
Authors:Carsten Finke  Eberhard Siebert  Michail Plotkin  Gregor K Wenning  Uwe Reuter
Affiliation:1. Department of Neurology, Charité – Universitätsmedizin Berlin, Campus Charité Mitte, Charitéplatz 1, D-10117 Berlin, Germany;2. Department of Neuroradiology, Charité – Universitätsmedizin Berlin, Germany;3. Department of Nuclear Medicine, Charité – Universitätsmedizin Berlin, Germany;4. Department of Neurology, Universitätsklinik für Neurologie, Innsbruck, Austria
Abstract:Multiple system atrophy (MSA) and multiple sclerosis (MS) are progressive neurological disorders with overlapping clinical signs and symptoms. However, due to the course of the disease and the age of onset both disorders are rarely differential diagnosis for each other. We here report the remarkable association of the two diseases in one patient. As MSA dominated the clinical presentation, diagnosis and therapy of MS were delayed. We discuss the clinical symptoms in our patient and highlight the features that allow to differentiate both diseases.
Keywords:Multiple sclerosis  Multiple system atrophy
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