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Lack of association between cerebral microbleeds and low serum cholesterol in patients with acute intracerebral hemorrhage
Authors:Dilek Necioglu Orken  Gulay Kenangil  Ender Uysal  Lale Gundogdu  Ethem Erginoz  Hulki Forta
Institution:1. Sisli Etfal Education and Research Hospital, Department of Neurology, Istanbul, Turkey;2. Sisli Etfal Education and Research Hospital, Department of Radiology, Istanbul, Turkey;3. Istanbul University Cerrahpa?a Medical Faculty, Department of Public Health, Istanbul, Turkey
Abstract:

Background

The association of cerebral microbleeds (CMBs) with intracerebral hemorrhage (ICH) is well known and its relationship with low serum cholesterol in ICH patients might be of interest.

Methods

A total of 105 patients with ICH were evaluated. In all subjects cholesterol levels were measured after 12 h of fasting and gradient-echo magnetic resonance imaging (GE-MRI) was performed for detecting CMBs.

Results

CMBs were more common among patients with hypertension and leukoaraiosis (p = 0.008 and p = 0.001). Patients with and without CMBs did not differ according to total cholesterol, LDL cholesterol, triglycerides and HDL cholesterol levels.

Conclusion

In this study, 61% of Turkish ICH patients had CMBs, which was not associated with lipid profiles. Leukoaraiosis was independently associated with CMBs.
Keywords:Cerebral microbleeds  Intracerebral hemorrhage  Hypocholesterolemia  Leukoaraiosis  Risk factor
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