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Role of palliative surgery in ovarian cancer
Institution:1. University of North Carolina at Chapel Hill, Gynecologic Oncology, United States;2. University of North Carolina at Chapel Hill, Lineberger Comprehensive Cancer Center, United States;3. University of North Carolina at Chapel Hill, School of Medicine, United States;1. Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, Rockville, MD, United States;2. Clinical Genetics Branch, Division of Clinical Epidemiology and Genetics, National Cancer Institute, Rockville, MD, United States;3. Biostatistics Branch, Division of Clinical Epidemiology and Genetics, National Cancer Institute, Rockville, MD, United States;4. Division of Gynecologic Oncology, Kaiser Permanente Medical Care Program, Oakland, CA, United States;5. Regional Laboratory, Kaiser Permanente Northern California, Berkeley, CA, United States;6. Department of Epidemiology & Population Health, Albert Einstein College of Medicine, Bronx, NY, United States;1. Department of Obstetrics and Gynecology, Section of Gynecologic Oncology, Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States;2. Department of Medicine, Division of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, United States
Abstract:The most common indication for palliative surgery in recurrent ovary cancer is malignant bowel obstruction. After careful diagnosis of bowel obstruction, conservative management should be employed. If resolution of obstruction does not occur, the decision to perform surgery must be made. Several authors have reported on outcomes in patients undergoing surgery. Operative morbidity and mortality is 7–64% and 4–32%, respectively, and median survival is 5–33 weeks in these reports. Surgery should be considered in select patients after a thorough discussion with the patient regarding the likely outcome following the procedure, including the potential for morbidity and mortality. The surgery should be aimed at relieving the symptoms and improving quality of life.
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