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The Enantioselective Binding of Mefloquine Enantiomers to P-glycoprotein Determined Using An Immobilized P-glycoprotein Liquid Chromatographic Stationary Phase
Authors:Lu  Lili  Leonessa  Fabio  Baynham  Michael T.  Clarke  Robert  Gimenez  Francois  Pham  Yen-Thu  Roux   Francoise  Wainer   Irving W.
Affiliation:(1) Department of Pharmacology, School of Medicine, Georgetown University, Department of Pharmacology, Room C305, Medical Dental Building, 3900 Reservoir Road, NW, Washington, DC, 20007;(2) Lombardi Cancer Center, Georgetown University, Washington, DC, 20007;(3) Pharmacie Clinique, University Paris XI, 5 rue Jean-Baptiste Clement, 92296 Chatenay-Malabry, France;(4) INSERM U26, Hospital Fernand Widal, 200 rue du Faubourg St Denis, 75475 Paris cedex 10, France
Abstract:Pharmaceutical Research -
Keywords:P-glycoprotein  enantiomers of mefloquine  dissociation constant of drugs  immobilized receptor  frontal affinity chromatography
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