安宫牛黄丸辅助治疗重型颅脑损伤的临床观察

目的 探讨安宫牛黄丸辅助治疗重型颅脑损伤的效果.方法 将格拉斯哥昏迷评分(GCS)<8分的颅脑损伤患者80例,随机分为观察组和对照组,每组40例,两组均给予常规治疗,观察组加用安宫牛黄丸治疗.比较两组治疗前及治疗3 d、5 d、7 d、14 d后GCS评分变化、并发症发生率、治疗3个月后的格拉斯哥预后评分.结果 治疗后两组GCS均随观察时间延长而升高,观察组GCS升高幅度大于对照组(均P<0.05);3个月后观察组预后优良率为60.53%(23/38),高于对照组的35.14%(13/37)(P<0.05);两组并发症发生率比较,差异无统计学意义(P>0.05).结论 安宫牛黄丸能促进颅脑损伤患者清醒,改善预后.

Clinical observation on Angong Niuhuang pill for adjuvant treatment of severe craniocerebral injury

Objective To investigate the effect of Angong Niuhuang pill for the adjuvant treatment of severe craniocerebral injury.Methods A total of 80 patients with craniocerebral injury and Glasgow Coma Scale(GCS) score<8 were randomly divided into observation group and control group,with 40 cases in each group.Both groups were given conventional treatment,while the observation group was treated with Angong Niuhuang pill additionally.GCS scores before treatment,at 3,5,7 and 14 days after treatment and the incidence rates of complications were compared between the two groups,and Glasgow Outcome Scale scores after 3 months of treatment were compared as well.Results After treatment,GCS scores increased with the increasing observation time in both groups,the increase of GCS scores in the observation group was greater than that in the control group(all P<0.05).After 3 months of treatment,the excellent and good rate of prognosis in the observation group was 60.53%(23/38),higher than that in the control group(35.14%,13/37;P<0.05).There were no significant differences in the incidence rates of complications between the two groups(P>0.05).Conclusion Angong Niuhuang pill can promote the mental alertness and improve the prognosis of patients with craniocerebral injury.