Rapid accumulation of eosinophils in lung lesions in guinea pigs infected with Mycobacterium tuberculosis |
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| Authors: | Lasco Todd M Turner Oliver C Cassone Lynne Sugawara Isamu Yamada Hiroyuki McMurray David N Orme Ian M |
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| Affiliation: | Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523, USA. Todd.Lasco@colostate.edu |
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| Abstract: | Guinea pig eosinophils were positively identified in bronchoalveolar lavage populations and in the lung granulomas of Mycobacterium tuberculosis-infected guinea pigs. It is possible that the rapid influx of these cells, and their subsequent degranulation during acute pulmonary tuberculosis, may play a key role in the susceptibility of this animal model. |
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