机械疏通联合医用聚乙二醇小檗碱液介入治疗输卵管阻塞性不孕

目的：探讨导丝机械疏通联合医用聚乙二醇小檗碱液介入治疗输卵管阻塞性不孕的临床价值。方法：在数字减影血管造影（DSA）机引导下，采用微导管、微导丝技术对31例输卵管阻塞的患者进行输卵管再通治疗，闭塞的输卵管疏通后注入医用聚乙二醇小檗碱液，记录输卵管再通成功率，患者不良反应等。结果：研究组31例62条，对照组30例60条全部开通。术后3天、1周及1个月妇科门诊通液研究组通畅率分别为100％、96．8％、93．5％；对照组分别为70％、80％、73．3％；两组通畅率组间比较差异有显著性意义（Х^2=10．91，P〈0．05；Х^2=4．23，P〈0．05；Х^2=4．55，P〈0．05）。3个月行子宫输卵管造影（HSG）检查，研究组成功率为90．3％、有效率为93．5％；对照组成功率为63．3％、有效率为80％；两组子宫输卵管疏通成功率及有效率组间比较差异有显著性意义（Х^2=6．3754，P〈0．05）；随访6个月～1年，研究组妊娠15例、受孕率为48．4％，对照组妊娠10例、受孕率为33．3％，研究组高于对照组。结论：采用微导管、微导丝机械疏通联合医用聚乙二醇小檗碱液灌注介入治疗输卵管阻塞，能有效促进组织生理修复，抑制炎性渗出，防止介入治疗术后再粘连，是一种可行的术式。

Mechanical Deoppilation with Guide Wire Combined with Medical Macrogol Berberine Solution for the Treatment of Infertility Due to Fallopian Tube Obstruction

Objective:To investigate the clinical value of mechanical deoppilation with guide wire combined with medical macrogol berberine solution for the treatment of infertility due to fallopian tube obstruction.Methods:Under the control of digital subtraction angiography (DSA),31 cases suffering from fallopian duct obstruction were treated by mechanical deoppilation with microtubule and micro-guide wire,then the medical macrogol berberine solution was injected into the recanalized fallopian tubes.The recanalizatio...