|
|||||
|
|
| HPLC-MS/MS联用技术分析鉴定苏薄荷中的黄酮类成分 | |
| 引用本文： | 林彤,段金廒,钱大玮,王大为,钱士辉.HPLC-MS/MS联用技术分析鉴定苏薄荷中的黄酮类成分[J].中国天然药物,2006,4(2):111-115. |
| 作者姓名： | 林彤 段金廒 钱大玮 王大为 钱士辉 |
| 作者单位： | 1. 广州市药品检验所,广州,510160;江苏省中医药研究院,南京,210028 2. 南京中医药大学,南京,210029 3. 江苏省中医药研究院,南京,210028 |
| 基金项目： | 国家重大科技专项基金;江苏省自然科学基金 |
| 摘 要： | 目的：分析鉴定苏薄荷中的黄酮类成分。方法：运用高效液相色谱分离与电喷雾（ESI）质谱技术对苏薄荷提取物中的黄酮类成分进行分析鉴定。结果：共分析了8个黄酮类成分，其中鉴定了1个黄酮苷元：香叶木素（diosmetin），4个黄酮苷：橙皮苷（hesperidin）、香叶木素-7-0-葡萄糖苷（diosmetin-7-0-glucoside）、蒙花苷（1inarin）、椴树素（tilianine），推断了2个黄酮苷和1个黄酮苷元的可能结构，其中橙皮苷、香叶木素-7-O-葡萄糖苷和香叶木素为首次从苏薄荷中发现。结论：HPLC-MS／MS能快速、准确地鉴定出天然产物中的化学成分。 |
| 关 键 词： | 苏薄荷 黄酮类成分 |
| 文章编号： | 1672-3651（2006）02-0111-05 |
| 收稿时间： | 2005-09-16 |
| 修稿时间： | 2005年9月16日 |
Identification of Flavonoids from Herb of Mentha haplocalyx by HPLC-MS/MS |
|
| LIN Tong,DUAN Jin-Ao,QIAN Da-Wei,WANG Da-Wei,QIAN Shi-Hui.Identification of Flavonoids from Herb of Mentha haplocalyx by HPLC-MS/MS[J].Chinese JOurnal of Natural Medicines,2006,4(2):111-115. | |
| Authors: | LIN Tong DUAN Jin-Ao QIAN Da-Wei WANG Da-Wei QIAN Shi-Hui |
| Institution: | 1. Guangzhou Institute for Drug Control, Guangzhou 510160; 2.Nanjing University of Traditional Chinese Medicine, Nanjing 210029 ; 3.Jiangsu Provincial Academy of Traditional Chinese Medicine, Nanjing 210028, China |
| Abstract: | AIM:To identifiy flavonoids from herb of Mentha haplocalyx Briq.METHOD:A quadrupole tandem mass spectrometer was applied to verify the structure of flavonoids from LC eluate by Q1 scan and product ion scan.RESULTS: One flavonoid aglycone and four flavonoid glycosides were determined and the possible structures of two flavonoid glycosides and one flavonoid aglycone were deduced based on the chromatography and mass data.Three of them were found from Mentha haplocalyx Briq.for the first time.CONCLUSION:This method could be available and helpful for the rapid discovery and identification of constituents from natural products. |
| Keywords: | HPLC-MS/MS |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |