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| 丹参对人成骨细胞缺血-再灌注损伤的保护作用 | |
| 引用本文： | 王福生,王立德,谷玲,宋淑云,洪新,李素凤.丹参对人成骨细胞缺血-再灌注损伤的保护作用[J].中国现代医学杂志,2000,10(5):1-3. |
| 作者姓名： | 王福生 王立德 谷玲 宋淑云 洪新 李素凤 |
| 作者单位： | 1. 大连医科大学附属第一医院,116011 2. 大连医科大学基础医学院骨科,116027 3. 辽阳市辽阳县中医院,111200 |
| 摘 要： | 观察丹参对成骨细胞缺血－再灌注损伤的保护作用。方法：以人髂骨骨膜为材料进行成骨细胞的体外培养，经丹参预处理后，行模拟缺血－再灌注采用唑蓝比色法测定细胞的夏活率。结果：预处理组成骨细胞的存活率明显高于对照组。结论：丹参对人成骨细胞缺血－再灌注有明显的保护作用。 |
| 关 键 词： | 丹参 成骨细胞 缺血－再灌注损伤 |
EXPERIMENTAL STUDY ON RADIX SALVIAE MILTIORRHIZAE (RSM) FOR THE PROTECTION OF HUMAN OSTEOBLAST AGAINST ISCHEMIA-REPERFUSION INJURY IN VITRO |
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| Wang Fusheng,Wang Lide,Gu Ling,Song Shuyun,Hong Xin,Li Shufeng.EXPERIMENTAL STUDY ON RADIX SALVIAE MILTIORRHIZAE (RSM) FOR THE PROTECTION OF HUMAN OSTEOBLAST AGAINST ISCHEMIA-REPERFUSION INJURY IN VITRO[J].China Journal of Modern Medicine,2000,10(5):1-3. | |
| Authors: | Wang Fusheng Wang Lide Gu Ling Song Shuyun Hong Xin Li Shufeng |
| Abstract: | Objective: To observe the effects of RSM precondition on human osteoblast being injuried by ischemia-reperfusion. Methods: Human osteoblasts were obtained by explanting the iliac periostenum cultured in DMEM media. Cultured osteoblasts were exposed to mimicking ischemia-reperfusion after a short time of RSM preconditioning. The cellular survival rate was determined with MTT method. Results: In preconditioning group, the osteoblast survival rate was significantly increased. Conclusion: RSM preconditioning can protect osteoblast against its ischemia-reperfusion injury. |
| Keywords: | Radix Salviae Miltiorrhizae (RSM) Human osteoblast Ischemia-reperfusion |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |