磁共振扩散加权和扩散张量成像在脑肿瘤诊断和评价中的作用

目的：探讨磁共振扩散加权（DWI）和扩散张量成像（DTI）在脑肿瘤的诊断和评估中的价值。方法：结合文献报道，对DWI和DTI在脑肿瘤诊断、鉴别诊断、分级、术前评估、手术计划制定以及对治疗随访中作用进行回顾性分析和评价。结果：DWI和DTI成像在脑肿瘤的诊断、鉴别诊断以及肿瘤的分级中具有一定的价值，DTI能够清晰显示肿瘤对白质柬的影响，对手术计划的制定具有重要意义，术中MRI、fMRI和DTI的结合使脑肿瘤手术更加合理。同时DTI也能将肿瘤对治疗的反应和治疗所致的白质变化进行准确评估。结论：随着MRI硬件和软件技术的发展，DWI和DTI成像提供的信息在脑肿瘤病变的诊断、评价、治疗指导与评估中起著重要作用．

Application of Diffusion-weighted MR Imaging and Diffusion Tensor Imaging in Brain Tumor Diagnosis and Evaluation

Objective To discuss the application of DWI and DTI in diagnosis and evaluation of brain tumor. Methods Combining with literatures, the application of DWI and DTI in brain tumor diagnosis, differential diagnosis, tumors classification, preoperative evaluation, operation plan establishment, follow-up role of treatment were reviewed and evaluated. Results The DWI and DTI were available to brain tumor diagnosis, differential diagnosis and tumor grade. The DTI could be clearly shown the influence of tumor with white matter quality, it was important in operation plan establishment. The combination of intra-operative MRI, functional MRI and DTI was valuable for brain tumor resection. In the meantime, the treatment response of tumor and the changes of treatment-induced white matter were accurately assessed by DTI. Conclusion With the MRI hardware and software technology development, the DWI and DTI imaging information can be provided important value in brain tumor pathological changes diagnosis, evaluation, therapeutic planning and post treatment assess- ment.[Chinese Medical Eauipment Journal, 2009,30（3） ： 71-73,76]