定量组织速度成像对左室心肌收缩功能的研究

目的 应用定量组织速度成像（QTVI）分析正常人及心肌梗死患者左室心肌收缩运动特征，探求评价心肌收缩功能的合理量化指标。方法 应用QTVI离线分析10例前壁心梗病人及20例正常对照者左室各节段长轴方向的心肌多普勒速度曲线，计算平均峰值收缩速度（Vs)、收缩加速度（a)、长轴收缩速度增加率（Rvi)等反映收缩功能的参数。结果 正常人左室长轴a由基底段到心尖逐渐减低，心肌梗死时这一规律丧失，梗死区a显著减小；包含梗死区的室壁Rvi与非梗死区及正常人相应室壁Rvi对比显著增大或减小。结论 （1）RTVI可全定量同步对比分析多室壁节段的运动。（2）a可直观反映心肌收缩性。（3）Rvi对比显著增大或减小。结论 （1）QTVI可全定量同步对比分析多室壁节段的运动。（2）a可直观反映心肌收缩性。（3）Rvi可人微言轻反映左室长轴收缩功能的量化指标。

Regional Systolic Function Estimation by Quantitative Tissue Velocity Imaging

Objective This study was designed to analyze and compare the leftventricular regional systolic function of normal subjects and patients with myocardial infarction,and explore the reasonable parameters to estimate regional systolic function.Methods The left ventricular regional long axis systolic velocity profiles of 18 patients and 20 normal subjects were analyzed with quantitative tissue velocity imaging(QTVI),and the regional mean systolic peak velocity(Vs)，systolic acceleration(a) and the rate of long axis systolic peak velocity increase(Rvi) were calculated.Results The left ventricular long axis acceleration has the highest value at the basal segment,and the smallest value at the apical segment,whereas this pattern is lost in MI patients.The systolic acceleration of infarcted segments is decreased dramatically.The Rvi of the infarcted wall is obviously larger or less than that of non-infarcted wall and the same wall of normal subjects.Conclusion ①QTVI can be used to analyze multi-segments motion quantitatively and synchronously.②Systolic acceleration can reflect myocardial contractility directly.③Rvi can be used as a quantitative parameter to assess the left ventricular long axis contractility.