| 正交法优选安宫牛黄微丸处方药材的醇提工艺 |
| |
| 引用本文： | 林瑶,雷国莲,王晓娟,顾宜,王荣,王荣华. 正交法优选安宫牛黄微丸处方药材的醇提工艺[J]. 解放军药学学报, 2010, 26(5): 397-399. DOI: 10.3969/j.Issn.1008-9926.2010.05.08 |
| |
| 作者姓名： | 林瑶 雷国莲 王晓娟 顾宜 王荣 王荣华 |
| |
| 作者单位： | 1. 陕西中医学院药学院,陕西咸阳,712046
2. 第四军医大学第三附属医院药剂科,陕西西安,710032 |
| |
| 基金项目： | 陕西省中医管理局;中医药科研课题 |
| |
| 摘 要： | 目的优选安宫牛黄微丸的最佳提取工艺。方法以干膏率和3种成分的含量（黄芩苷、栀子苷、盐酸小檗碱）为检测指标,以乙醇浓度、用量、提取时间、提取次数为考察因素,采用正交试验优选最佳提取工艺。结果最佳提取工艺为12倍量70%的乙醇溶液,回流提取3次,2h/次。结论该工艺简便,稳定,合理,可用于工业化生产。
|
| 关 键 词： | 提取工艺 正交试验 安宫牛黄微丸 |
Optimization of the Alcohol Extraction Technology of Prescription Drugs in Angongniuhuang Pellets by Orthogonal Experiment |
| |
| LIN Yao,LE Guo-lian,WANG Xiao-juan,GU Yi,WANG Rong,WANG Rong-hua. Optimization of the Alcohol Extraction Technology of Prescription Drugs in Angongniuhuang Pellets by Orthogonal Experiment[J]. Pharmaceutical Journal of Chinese People's Liberation Army, 2010, 26(5): 397-399. DOI: 10.3969/j.Issn.1008-9926.2010.05.08 |
| |
| Authors: | LIN Yao LE Guo-lian WANG Xiao-juan GU Yi WANG Rong WANG Rong-hua |
| |
| Affiliation: | (①College of Pharmacy,Shaanxi College of Traditional Chinese Medicine,Xianyang712046,China;②Third Affiliated Hospital,Fourth Military Medical University,Xi＇an710032,China ) |
| |
| Abstract: | Objective To optimize the extraction technology of Angongniuhuang pellets.Methods The ratio of dry extraction and the content of three ingredients（baicalin,geniposide,berberine hydrochloride）were used as the index.The orthogonal test was used for studying the effect of the concentration of alcohol,amount of alcohol,extraction time,number of extraction times on the content.Results The optimial preparation condition was to add 12 times as much alcohol of the concentration of 70%.The reflow extraction was 3 times,2 hours each time.Conclusion This technique is simple,stable,reasonable,and can be used for industrial production. |
| |
| Keywords: | extraction technology orthogonal test Angongniuhuang pellets |
| 本文献已被 维普 万方数据 等数据库收录！ |
|
