Affiliation: | a Cognitive Impairment Center, General Hospital of Treviso, Piazza Ospedale, 1, I-31100 Treviso, Italy b Department of Statistics University of Padova, Via Cesare Battisti, 241, I-35121 Padova, Italy c Dementia Research Center, The Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA d Neuropsychiatric Epidemiology Unit, Sahlgrenska Academy, University of Gothenburg, Sweden e Department of Neuroscience, “Mario Negri” Institute for Pharmacological Research, via La Masa 19, I-20156 Milan, Italy f Transfusional Department, General Hospital of Treviso, Piazza Ospedale, 1, I-31100 Treviso, Italy g Department of Pathology, General Hospital of Treviso, Piazza Ospedale, 1, I-31100 Treviso, Italy i FORGEI, Interdisciplinary Geriatric Research Foundation, Trento Trieste Aven. 19, I-31100 Treviso, Italy |
Abstract: | Prolongation of life is an important public health goal as long as there is an emphasis on the quality of life (QoL) and independent living. Diminishing abilities to ambulate and participate in activities of daily living point to a serious decline in functional health, increasing the risk of institutionalization and death. In our work we found a pattern of factors associated with disability, especially cognitive impairment, as well as stroke, physical activity and performance, reading, and the nutritional biomarkers, blood albumin and high-density lipoprotein cholesterol (HDL-C). The attention to this cluster of markers, suggesting multidimensional prevention, may have unexpected good effects against disability. |