新生儿脓毒症研究进展

新生儿脓毒症是新生儿期细菌或真菌侵入血液循环并在其中生长繁殖,产生毒素所造成的全身性感染.目前该类疾病的发病率和病死率仍占新生儿感染性疾病首位.根据新生儿自身特点该类疾病的临床表现不明显,给临床带来了一系列问题.本文就新生儿脓毒症的流行病学、病因、病理生理、临床特点及与成人脓毒性休克的异同点等方面作一综述,以加深对新生儿脓毒症的认识.

Advance on the neonatal sepsis

Neonatal sepsis is a systemic infection in which bacteria or fungi invade blood circulation and grow in it in the neonatal period,caused by toxin produce from bacteria or fungi.Currently sepsis is the major causing morbidity and mortality in neonatal infectious diseases,its clinical manifestation is not obvious and this brings us a range of clinical problems.In this review,we discussed these characteristics epidemiology,etiology,pathophysiology,clinical features of neonatal sepsis and septic shock in adults,to deepen the understanding of neonatal sepsis.