| 吲哚美辛直肠给药治疗腹部手术后疼痛120例 |
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| 引用本文： | 刘加升. 吲哚美辛直肠给药治疗腹部手术后疼痛120例[J]. 中国新药与临床杂志, 1998, 0(2) |
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| 作者姓名： | 刘加升 |
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| 作者单位： | 沛县中医院 |
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| 摘 要： | 目的：观察吲哚美辛直肠给药与曲马多肌内注射对腹部手术后疼痛的疗效比较。方法：１２０例腹部术后病人，男性８６例，女性３４例；年龄４１±ｓ８ａ，给予吲哚美辛混悬液５ｍＬ（７５ｍｇ）直肠给药。另有腹部手术后病人６０例，男性４１例，女性１９例；年龄４３±９ａ，用曲马多１００ｍｇ肌内注射。２组作随机单盲对照试验。结果：吲哚美辛组止痛作用优于曲马多组，总有效率分别为９２．５％和８２％（Ｐ＜０．０５）。吲哚美辛组平均镇痛有效持续时间９±５ｈ，优于曲马多组７±３ｈ（Ｐ＜０．０１）。结论：吲哚美辛直肠给药治疗腹部手术后疼痛疗效满意。
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| 关 键 词： | 吲哚美辛；曲马多；止痛；直肠内投药；手术后疼痛 |
Rectal administration of indometacin in treating abdominal postoperative pain in 120 patients |
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| LIU Jia_Sheng. Rectal administration of indometacin in treating abdominal postoperative pain in 120 patients[J]. Chinese Journal of New Drugs and Clinical Remedies, 1998, 0(2) |
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| Authors: | LIU Jia_Sheng |
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| Abstract: | AIM: To observe the efficacy of indometacin in treating abdominal postoperative pain. METHODS: One hundred and twenty patients (M 86, F 34, age 41±s 8 a) suffering from abdominal postoperative pain were treated with rectal administration of indometacin suspension 5 mL (15 mg/mL). Another 60 patients (M 41, F 19, age 43±9 a) were treated with tramadol 100 mg, im, as control. RESULTS: The pain_relief effective rate in indometacin group was 92.5%, higher than that (82%) of tramadol group (P<0.05). The pain_relief lasting_time in indometacin group was 9±5 h, longer than that (7±3 h) of control (P<0.01). CONCLUSION: The efficacy of indometacin in treating abdominal postoperative pain is satisfactory. |
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| Keywords: | indometacin tramadol analgesia rectal administration postoperative pain |
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