| 垂体腺瘤108例临床病理分析 |
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| 引用本文： | 李小静,武景波,许祖德,滕昊骅. 垂体腺瘤108例临床病理分析[J]. 临床与实验病理学杂志, 2011, 27(12) |
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| 作者姓名： | 李小静 武景波 许祖德 滕昊骅 |
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| 作者单位： | 1. 复旦大学附属上海市第五人民医院病理科,200240
2. 复旦大学附属华山医院病理科,上海,200040 |
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| 摘 要： | 目的研究垂体腺瘤的临床、病理学及预后特点。方法收集2005年5月～2007年12月复旦大学附属上海第五人民医院神经外科病理确诊的垂体腺瘤患者108例,回顾性分析其临床、放射学、随访资料及HE染色、免疫组化染色等临床病理特点。结果 108例患者中,男性45例,女性63例,发病年龄17～89岁,平均48.0岁。根据影像学显示大小,分为微腺瘤18例,大腺瘤87例,巨大腺瘤3例。依据免疫组化结果显示生长激素(growth hormone,GH)型腺瘤50例,泌乳激素(prolactin,PRL)型腺瘤28例,促肾上腺皮质激素(adenocorticotropic hormone producing adenoma,ACTH)型腺瘤11例,促性腺激素(gona-dotropin producing adenoma,FSH/LH)型腺瘤10例,裸细胞腺瘤(null cell adenoma)4例,其它混合型腺瘤5例。患者术后随访时间30～60个月,平均43.9个月,其中36例(33.3%)复发。结论肿瘤复发与肿瘤大小及切除完整与否有关(P<0.05),与患者年龄、性别及肿瘤免疫表型、是否侵袭无关(P>0.05)。免疫组化...
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| 关 键 词： | 垂体腺瘤 病理学 预后 免疫组化 |
Pituitary adenoma: clinicopathologic analyses of 108 cases |
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| LI Xiao-jing,WU Jing-bo,XU Zu-de,TENG Hao-hua. Pituitary adenoma: clinicopathologic analyses of 108 cases[J]. Chinese Journal of Clinical and Experimental Pathology, 2011, 27(12) |
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| Authors: | LI Xiao-jing WU Jing-bo XU Zu-de TENG Hao-hua |
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| Affiliation: | LI Xiao-jing1,WU Jing-bo1,XU Zu-de2,TENG Hao-hua1(1Department of Pathology,Fifth People's Hospital,Fudan University,Shanghai 200240,China,2Department of Pathology,Huashan Hospital,Shanghai 200040,China) |
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| Abstract: | Purpose To study the clinical,histopathological and prognostic characteristics of pituitary adenoma.Methods A retrospective analysis were performed by review of clinical,radiological and prognostic data and hematoxylin-eosin and immunohistochemical stains in 108 cases of pituitary adenoma from May 2005 through December 2007.Results Of the 108 cases in our series,45 were males and 63 females.The mean age at presentation was 48.0 years(range 17~89 years).By magnetic resonance,18 cases were microadenomas,87 we... |
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| Keywords: | pituitary adenoma pathology prognosis immunohistochemistry |
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