首页 | 本学科首页   官方微博 | 高级检索  
     

不稳定性心绞痛与血管活性肽的相关性
引用本文:王文清,刘朝中,谈维洁,孙晓丽,黄从春,毛树森,江一清. 不稳定性心绞痛与血管活性肽的相关性[J]. 心脏杂志, 2000, 12(3): 172-173. DOI: 10.13191/j.chj.2000.03.10.wangwq.003
作者姓名:王文清  刘朝中  谈维洁  孙晓丽  黄从春  毛树森  江一清
作者单位:空军总医院心血管内科,北京,100036
摘    要:目的 :探讨不稳定性心绞痛 (UAP)与血管活性肽的相关性。方法 :观察 42例 UAP患者心绞痛发作前后血浆内皮素 (ET)、降钙素基因相关肽 (CGRP)、神经肽 Y (NPY)及 P物质 (SP)的变化 ,并和 2 0例正常人对照。结果 :当心绞痛发作时 ,UAP患者血浆 ET,NPY,SP均较前明显升高 (P<0 .0 5 ) ,CGRP含量下降 ;随着心绞痛的缓解 ,血浆 CGRP开始升高 ,ET,NPY和 SP均于 3 d后恢复至发作前水平。结论 :U AP的发生与血管活性肽的变化密切相关 ,血管活性肽对维持冠脉舒张和循环有重要意义

关 键 词:心绞痛  不稳定型   血浆内皮素   降钙素基因相关肽   神经肽Y   P物质

The relation of plasma vasoactive peptide concentration with UAP
WANG Wen-qing,LIU Chao-zhong,TAN Wei-jie,SUN Xiao-li,HUANG Cong-chun,MAO Shu-sen,JIANG Yi-qing. The relation of plasma vasoactive peptide concentration with UAP[J]. Chinese Heart Journal, 2000, 12(3): 172-173. DOI: 10.13191/j.chj.2000.03.10.wangwq.003
Authors:WANG Wen-qing  LIU Chao-zhong  TAN Wei-jie  SUN Xiao-li  HUANG Cong-chun  MAO Shu-sen  JIANG Yi-qing
Abstract:AIM:To probe into relation beween unstable angina pectoris (UAP) and vasoactive peptide. METHODS:We investigated the variation of plasma concentration of endothelin (ET), calcitonin gene related peptide (CGRP),neuropeptide Y (NPY) and substance P (SP) in 42 patients with UAP and 20 healthy subjects. RESULTS:When angina pectoris attacked ET,NPY,SP increased ( P <0.05). Concentration of CGRP decreased. After angina pectoris was relieved,ET,NPY and SP concentration decreased to pre angina pectoris level in 3 days but CGRP concentration was still high. CONCLUSION:The variation of plasma vasoactive peptide concentration was not only related to UAP attack but also significant to the maintance coronary diastole and corculation.
Keywords:angina  unstable  endothelin  calcitonin gene related peptide  neuropeptide Y  substance P
本文献已被 CNKI 维普 万方数据 等数据库收录!
点击此处可从《心脏杂志》浏览原始摘要信息
点击此处可从《心脏杂志》下载全文
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号