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高原肺水肿患者血清肌钙蛋白T研究
引用本文:王洪斌,李素芝,姚文新,周晓波,郑必海. 高原肺水肿患者血清肌钙蛋白T研究[J]. 西南国防医药, 2004, 14(4): 367-369
作者姓名:王洪斌  李素芝  姚文新  周晓波  郑必海
作者单位:西藏军区总医院实验中心,西藏,拉萨,850003
摘    要:目的 :探索高原肺水肿 (HAPE)患者血清肌钙蛋白 T(cTnT)的变化。方法 :放免法测定HAPE患者在一氧化氮(NO)治疗前后血清cTnT。结果 :cTnT治疗前显著高于治疗后 (P <0 0 1) ,SaO2 治疗后显著高于治疗前 (P <0 0 0 1) ,治愈率为 10 0 0 %。结论 :对较重的HAPE患者有心肌损害和心功能的下降 ;NO治疗HAPE是非常有效的 ,为HAPE治疗提供了新的方法

关 键 词:高原  肺水肿  肌钙蛋白-T
文章编号:1004-0188(2004)04-0367-03
修稿时间:2004-05-19

Research of serum cardiac troponin T in patients with high altitude pulmonary edema
WANG Hong - bin,LI Su - zhi,YAO Wen - xin,ZHOU Xiao - bo,ZHENG Bi - hai.Experimental Center,General Hospital of Tibet Military Command,Lhasa,.. Research of serum cardiac troponin T in patients with high altitude pulmonary edema[J]. Medical Journal of National Defending forces in Southwest China, 2004, 14(4): 367-369
Authors:WANG Hong - bin  LI Su - zhi  YAO Wen - xin  ZHOU Xiao - bo  ZHENG Bi - hai.Experimental Center  General Hospital of Tibet Military Command  Lhasa  .
Affiliation:WANG Hong - bin,LI Su - zhi,YAO Wen - xin,ZHOU Xiao - bo,ZHENG Bi - hai.Experimental Center,General Hospital of Tibet Military Command,Lhasa,850003.
Abstract:Objective: To detect the changes of serum cardiac troponin T(cTnT) in patients with high altitude pulmonary edema(HAPE). Methods: The levels of cTnT in patients with high altitude pulmonary edema were determined by radiaoimmunoassay before and after treated with nitrogen monoxide(NO). Results: The level of cTnT in HAPE subjects before NO treatment was higher than that after NO treatment(p<0.01), and blood oxygen saturation(SaO2) in finger before NO treatment was lower than that after NO treatment(p<0.01). The cure rate for HAPE with NO was 100%.Conclusion: There was myocardial damage and heart function fall in HAPE cases, and NO might be a very effective therapeutic drug to this disease.
Keywords:high altitude   pulmonary edema   cardiac troponin T   treatment
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