应变率成像评价冠心病左心房功能的初步研究

目的探讨应变率成像评价冠心病左心房局部功能的价值。方法应用应变率成像与常规超声心动图测量20例正常人与14例左心房内径正常的冠心病患者的左心房侧壁和房间隔应变率、左心房内径、二尖瓣口血流频谱E峰、A峰和E／A值以及右上肺静脉血流频谱S峰、D峰、A峰和A波持续时间，比较两组测量结果。结果两组左心房内径、二尖瓣口血流频谱值以及肺静脉血流频谱值之间的差异均无统计学意义，而两组左心房侧壁和房间隔应变率之间的差异具有统计学意义（P〈0．05）。结论应变率成像能够在左心室舒张功能尚无明显改变的情况下，早期发现左心房局部功能的异常。

Primary study of strain rate imaging in the assessment of the left atrial function in patients with coronary artery disease

Objective To evaluate left atrial(LA) local function in patients with coronary artery disease(CAD) by strain rate imaging(SRI).Methods LA lateral and septal strain rate,LA internal diameter,the peak flow velocities during early diastole(E),atrial contraction(A),E/A ratio,and peak velocity of right upper pulmonary venous flow(PVs,PVd and PVa)and A duration(ADT) were measured in 20 normal subjects and 14 patients with CAD but without left atrial dilatation by SRI and traditional echocardiography,and the results of the two groups were compared.Results Compared with control group,LA internal diameter,mitral valve flow pattern and pulmonary venous flow pattern were not significantly different.LA lateral and septal strain rate were significantly different between CAD group and control group(P< 0.05 ).Conclusions LA local dysfunction is able to be detected by strain rate imaging in patients without other echocardiographic features of cardiac diastolic function involvement.