中青年住院高血压患者服药依从性的影响因素

目的 调查中青年高血压住院患者的服药依从性及服药依从性的影响因素,探讨服药依从性与高血压、甘油三酯、HCY、血尿酸及PWV的相关性.方法 运用Morisky量表,采用便利抽样选取300例中青年住院高血压患者,并调查其服药依从性,运用单因素分析服药依从性与高血压、甘油三酯、HCY、血尿酸及PWV的关系,多因素Logistic回归分析服药依从性的影响因素.结果 中青年住院高血压患者的服药依从率为34%;服药不依从率为66%;多因素Logistic分析:文化程度、工作状态及高血压分层是住院中青年高血压患者服药依从性的影响因素;比较两组患者的高血压收缩压(148.5±16.39 vs 157.68±19.17);舒张压(89.71±13.35 vs 93.58±15.25)、甘油三酯(1.38±0.79 vs 1.68±1.27)、HCY(13.04±3.53 vs 15.36±6.91)、血尿酸(281.29±101.32 vs 343.11±114.43)及PWV(1699.8±346.14 vs 1795.1±395.39)、近3个月急诊次数(0.471±0.609 vs 0.773±1.46)、近3个月平均住院日(9.2±3.3 vs 10.4±4.2)及并发症种类(2.24±1.5 vs 2.95±1.54)差异均有统计学意义(均P<0.05).结论 文化程度越高、工作状态越规律、高血压分层越高的患者服药依从性越好;服药依从性佳的患者血压控制、相关临床生化指标调节较好且并发症种类及近3个月急诊次数和平均住院日较少.因此,医护人员应该加强中青年患者规律服药的健康宣教;提高中青年患者的服药依从率从而降低相关危险因素对血压的影响.

The influencing factors for the medication compliance of young and middle-aged hy-pertensive inpatients

Objective To investigate the medication compliance and the influencing factors of medication ad-herence of young and middle-aged hospitalized hypertension patients, and discuss the correlation between medication adherence with clinic blood pressure, triglycerides, HCY, blood uric acid, and PWV. Methods Using the Morisky scale, a total of 300 cases of young and middle-aged hospitalized hypertension patients were selected as the research ob-jects by taking convenience sampling method. All the patients'medication compliance were investigate. The relationship among the medication adherence and clinic blood pressure, triglycerides, HCY, blood uric acid and PWV were analyzed by using single factor analysis, and the influencing factors of medication adherence were analyzed by using multivariable Logistic regression analysis. Results The compliance rate of the young and middle-aged hospitalized hypertension pa-tients was 34%;the noncompliance rate was 66%; multivariable Logistic analysis: education degree, work status and hypertension layer was the influencing factors of the medication compliance of young and middle-aged hospitalized hyper-tension patients. The patients' SBP ( 148. 5 ± 16. 39 versus 157. 68 ± 19. 17 ) , DBP ( 89. 71 ± 13. 35 versus 93. 58 ± 15. 25), triglycerides (1. 38±0. 79 versus 1. 68±1. 27), HCY (13. 04±3. 53 versus 15. 36±6. 91), blood uric acid (281. 29±101. 32 versus 343. 11±114. 43), PWV (1699. 8±346. 14 versus 1795. 1±395. 39), the number of emer-gency in 3 months (0. 471±0. 609 versus 0. 773±1. 46), average length of stay in the nearly three months (9. 2±3. 3 versus 10. 4±4. 2) and kinds of complications (2. 24±1. 5 versus 2. 95±1. 54) of the two groups were compared, the differences were statistically significant ( P<0. 05 ) . Conclusion Patients with higher education degree, regularity working status, higher stratification of hypertension have better medication compliance; patients with better medication compliance have stable blood pressure, good clinical biochemical indexes, less kinds of complication, less emergency in nearly three months, and less average length of stay. Therefore, medical workers should strengthen the health educa-tion of young and middle-aged patients with regular medication, and increase the rate of medication compliance, so as to reduce the effects of risk factors related to blood pressure.