碱性成纤维细胞生长因子和白糖治疗褥疮的比较研究

目的：探讨碱性成纤维细胞生长因子和白糖对褥疮患者创面修复情况的影响。方法将我院2013年7月至2014年1月收治的褥疮患者38例，随机分为两组，在积极基础护理、彻底清创基础上，分别应用碱性成纤维细胞生长因子、白糖对创面进行处理，比较两组患者治疗显效时间以及14 d时治疗效果。结果两组患者治疗显效时间比较差异有统计学意义( P<0．05)，而14 d时治疗效果差异无统计学意义( P>0．05)。结论对褥疮患者在彻底清创基础上，采用白糖外用换药和碱性成纤维细胞生长因子外用换药对创面愈合均有积极作用，有一定效果，但碱性成纤维细胞生长因子起效较快。

Comparative study of bFGF and sugar care in treating pressure ulcers

Objective To compare and study the differences and effects of basic fibroblast growth factor ( bF-GF) and sugar care for the restoration of wound's surface of patients with pressure ulcers. Methods A total of 38 pa-tients with pressure ulcers in our hospital from July 2013 to January 2014 were randomly divided into two groups. The wound's surface of the two groups were treated by bFGF and sugar respectively on the basis of an active primary care and complete debridement. The effect initiating time and therapeutic effect after 14 days of the two groups were com-pared. Results There were statistically differences for effective initiating time, but no obviously statistically differences for the treatment effect after 14 days between the two groups. Conclusions Sugar and bFGF both have positive effects and therapeutic effects on the wound healing of pressure ulcers based on the complete debridement, but bFGF took effect rapidly.