穴位刺激对化疗引起恶心呕吐的效果评价

目的 评价国内文献穴位刺激对化疗引起恶心、呕吐的效果.方法 计算机检索中国生物医学文献数据库、中国期刊全文数据库、万方数据库、维普中文科技期刊全文数据库,纳入符合条件的随机对照试验(RCT),共纳入27个RCT.结果 Meta分析显示,与未进行穴位刺激相比,穴位刺激可降低化疗引起的急性呕吐的发生率.由于异质性,各研究关于穴位刺激对化疗引起恶心、延迟性呕吐的作用效果未能合并,各研究结论不一.16个RCT未能区分化疗引起恶心、呕吐的类型,而穴位刺激在观察期间是否能缓解化疗引起的呕吐症状,结论不一致.结论 穴位刺激可降低化疗引起急性呕吐的发生率.对急性恶心、延迟性恶心、呕吐、预期性恶心、呕吐的作用仍需高质量、设计严谨的临床试验来验证.

The effects of acupoint stimulation to the nausea and vomiting caused by chemother-apy

Objective To evaluate the effectiveness of acupoint stimulation on chemotherapy-induced nausea and vomiting ( CINV) of domestic and foreign literatures. Methods A total of 27 RCTs in accordance with inclusion criteria were enrolled in the study by searching databases from China Biology Medicine ( CBM ) , Chinese National Knowledge Infrastructure ( CNKI) , Wan Fang and VIP. Results The Meta analysis showed that acupoint stimulation could reduce the incidence rate of chemotherapy-induced acute vomiting. The effects of acupoint stimulation on chemo-therapy-induced nausea and delayed vomiting of researchs could not be pooled due to heterogeneity, and the conclusions were different. There were 16 RCTs whom couldn't distinguish the classification of chemotherapy-induced nausea and vomiting. The conclusions were different in whether acupoint stimulation can ease the chemotherapy-induced nausea and vomiting during the observation period. Conclusion Acupoint stimulation can reduce the incidence of chemotherapy-induced acute vomiting. More well-designed clinical trials are needed to verify the effectiveness of acupoint stimulation on other categories of CINV.