实时灰阶超声造影在宫腔异常回声鉴别诊断中的应用

目的探讨实时灰阶超声造影技术对宫腔异常回声鉴别诊断的应用价值。方法以意大利Bracco公司生产的声诺维（SonoVue）为造影剂，对27例宫腔异常回声者行实时灰阶超声造影检查，观察造影剂在病灶内充盈方式及增强程度，以手术病理结果为标准，分析比较不同病因的宫腔异常回声造影显像特点。结果27例宫腔异常回声的组织病理结果分别为子宫内膜息肉、子宫黏膜下肌瘤、子宫内膜癌、不全流产宫腔残留和宫腔黏连，各种病变的超声造影表现明显不同。结论实时灰阶超声造影技术能够较准确地鉴别诊断宫腔异常回声。

Application of real-time gray-scale contrast-enhanced ultrasonography in differential diagnosis of uterine cavity abnormalities

Objective To investigate the clinical value of real-time gray-scale contrast-enhanced ultrasonography （RT-CEUS） in differential diagnosis of intrauterine abnormalities. Methods Intravenous RT-CEUS by injecting Sonovue （Bracco, Milan, Italy） was performed in 27 patients with uterine cavity abnormalities diagnosed by transabdominal and transvaginal sonography. The pattern and sequence of contrast agent appearing in the lesions were focused. The results were compared with the histologic findings. Results Histologic findings of these 27 cases included endometrial polyps, uterus submucous myoma, endometrial cancer and intrauterine residual, intrauterine adhesions. Contrast-enhanced sonographic patterns were significantly different between these 5 pathologic type lesions. Conclusions RT-CEUS may have potential clinical value for differentiating intrauterine abnormalities.