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| 双黄连泡腾片干法制粒工艺研究 | |
| 引用本文： | 魏筱华,赖伊姗,黄恺,张尧,罗晓健.双黄连泡腾片干法制粒工艺研究[J].中国实验方剂学杂志,2010,16(11):1-5. |
| 作者姓名： | 魏筱华 赖伊姗 黄恺 张尧 罗晓健 |
| 作者单位： | 1. 南昌大学第一附属医院,南昌,330006 2. 九江市卫生学校,江西九江,332005 3. 中药固体制剂制造技术国家工程研究中心,南昌,330006 |
| 基金项目： | 国家"十一五"科技支撑计划项目，江西省卫生厅科技计划项目 |
| 摘 要： | 目的:研究双黄连泡腾片干法制粒的工艺条件。方法:考察轧轮压力、轧轮转速和浸膏粉含水量对颗粒得率和颗粒脆碎度的影响。结果:轧轮压力、轧轮转速和浸膏粉含水量对颗粒得率和颗粒脆碎度有显著性影响。结论:双黄连泡腾片干法制粒工艺的研究为双黄连泡腾片研究与生产提供技术参考。 |
| 关 键 词： | 双黄连泡腾片 干法制粒 轧轮压力 轧轮转速 浸膏粉含水量 |
| 收稿时间： | 2010/4/22 0:00:00 |
Study on Dry Granulation Technique for Shuanghuanglian Effervescent Tablets |
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| WEI Xiao-hu,LAI Yi-shan,HUANG Kai,ZHANG Yao and LUO Xiao-jian.Study on Dry Granulation Technique for Shuanghuanglian Effervescent Tablets[J].China Journal of Experimental Traditional Medical Formulae,2010,16(11):1-5. | |
| Authors: | WEI Xiao-hu LAI Yi-shan HUANG Kai ZHANG Yao and LUO Xiao-jian |
| Institution: | The First Affiliated Hospital of Nangchang University, Nanchang 330006,China;Health School of Jiujiang,Jiujiang 332005, China;Nationl Pharmaceutical Engineering Center for Soild Preparation in Chinese Herbal Medicine, Nanchang 330006, China;Nationl Pharmaceutical Engineering Center for Soild Preparation in Chinese Herbal Medicine, Nanchang 330006, China;Nationl Pharmaceutical Engineering Center for Soild Preparation in Chinese Herbal Medicine, Nanchang 330006, China |
| Abstract: | Objective: Research the best technology of Shuanghuanglian Effervescent Tablets by dry granulation. Method: Inspect the influence of roller press, roller speed and the water content of extract powder on yield and friability of particle diameter. Result: The roller press, roller speed and the water content of extract powder had a significant degree of influence. Conclusion: The investigation of Shuanghuanglian Effervescent Tablets by dry granulation would provide the reference technology for study and production of Shuanghuanglian Effervescent Tablets. |
| Keywords: | Shuanghuanglian Effervescent Tablets dry granulation the roller press roller speed the water content of extract powder |
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