Echocardiographic evaluation in patients with hypogonadotropic hypogonadism

OBJECTIVE: To assess cardiac function in patients with hypogonadotropic hypogonadism. STUDY DESIGN: We studied heart structure and left ventricular systolic and diastolic function by echocardiography in 38 patients with hypogonadotropic hypogonadism (34 men and 4 women, mean age 24 +/- 4 years) and in 30 healthy subjects (25 men and 5 women, mean age 22 +/- 3 years). Left ventricular end-diastolic diameter, end-systolic diameter, left ventricular septal wall thickness, posterior wall thickness and ejection fractions were measured by M-mode echocardiography. Parameters of mitral flow were measured by pulsed wave Doppler echocardiography. RESULTS: Between patients with and without hypogonadotropic hypogonadism, there were no significant differences in echocardiographic measurements. CONCLUSION: Cardiac function is normal in patients with hypogonadotropic hypogonadism.