| 注射用熊胆粉质量标准研究 |
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| 引用本文： | 朴惠善,朴宪,南善姬.注射用熊胆粉质量标准研究[J].辽宁中医杂志,2005,32(11):1189-1190. |
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| 作者姓名： | 朴惠善 朴宪 南善姬 |
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| 作者单位： | 1. 延边大学医学院,吉林,延吉,133000
2. 延边州药品检验所,吉林,延吉,133000 |
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| 摘 要： | 目的:建立注射用熊胆粉质量控制方法。方法:采用薄层色谱法对制剂中熊胆进行定性鉴别:用HPLC法测 定制剂中牛磺熊去氧胆酸含量。结果:薄层色谱中斑点清晰,易于识别:HPLC法精密度、重现性良好,牛磺熊去氧胆酸在 2．5～16μg内均较好的线性关系,加样回收率为99．75％,RSD为0．82％。结论:该法可有效控制注射用熊胆粉质量。
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| 关 键 词： | 注射用熊胆粉 牛磺熊去氧胆酸 高效液相色谱法 薄层色谱法 |
| 文章编号： | 1000-1719(2005)11-1189-02 |
| 收稿时间： | 2005-05-09 |
| 修稿时间： | 2005年5月9日 |
Study of Quality Standard for Injectable XIONGDAN Powder |
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| PIAO Hui-shan,PIAO Xian,NAN Shan-ji.Study of Quality Standard for Injectable XIONGDAN Powder[J].Liaoning Journal of Traditional Chinese Medicine,2005,32(11):1189-1190. |
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| Authors: | PIAO Hui-shan PIAO Xian NAN Shan-ji |
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| Institution: | 1. Medical College ofYanbian University, Yanji 133000, Jilin, China; 2. Institute for Drug Control in Yanbian Autonomic Canton, Yanji 133000 Jilin, China |
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| Abstract: | Objective:To establish method of quality control of injectable XIONGDAN powder. Methods:TLC was used to identify mjectable XIONGDAN powder. The content of tauroursodeoxycholic acid in mjectable XIONGDAN powder was determined by HPLC. Results:The spot in TLC was clear, easy to be recognized. HPLC was good in precision and reproducibility. HPLC exhibited a fine linear -esponse of tauroursodeoxycholic acid ranged from 2.5-16μg. The average recovery was 99.75%, RSD 0.82%. Conclusion: The method can control the quality of injectable XIONGDAN powder effectually. |
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| Keywords: | injectable XIONGDAN powder tauroursodeox-ycholic acid HPLC TLC |
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