大鼠原位肝移植模型手术方法的研究进展

大鼠原位肝移植模型的手术方法经历了近40年的发展,从最初的近似人的复杂手术方法,逐步经历了单袖套法、二袖套法、三袖套法和改良二袖套法等多种方法。不同的手术方法对大鼠肝移植的成功率和移植后的成活率影响较大。目前对手术方法的选择存在许多争议,现通过系统地描述大鼠原位肝移植模型手术方法的发展过程,总结近年来手术方法的研究进展及存在的问题,为选择恰当的手术方法提供参考。

Research Progress of Surgical Methods in Orthotopic Liver Transplantation Rat Model

Rat orthotopic liver transplantation model surgery has developed nearly 40 years,from the initial complex surgical techniques approximate to human surgery,to single-cuff,two-cuff,three-cuff and improved two-cuff technique and other methods.Selection of different surgical methods impacts greatly on the success rate and survival rate after transplantation in rats,where great controversy still exists.Therefore,here is to make a systematic review on the development of the surgical methods development and summarize progress and the existing problems in recent years to provide references for surgery method selection.