液基细胞学与巴氏涂片对宫颈病变诊断价值的临床观察

目的探讨液基细胞学与巴氏涂片在宫颈病变中的诊断价值。方法将7600例进行宫颈细胞学检查的妇女随机分为两组：观察组（3800例）应用液基细胞学检查，对照组（3800例）应用巴氏涂片检查。结果观察组宫颈上皮内瘤变阳性率17．26％（656／3800）]与组织病理学符合率96．34％（632／656）]明显高于对照组分别为12．24％（465／3800）、87．53％（407／465）]，差异均有统计学意义（P〈0．01或〈0．05），但滴虫检出率两组比较差异无统计学意义（P〉0．05）。结论对宫颈病变的筛查中，液基细胞学检查明显优于巴氏涂片，且方法简单、实用，临床应积极开展。

The diagnostic observation on thinprep cytologic test and Pap smear in cervical disease

Objective To observe the diagnostic value of thinprep cytologic test （TCT） and Pap smear in cervical disease. Methods The cervix cytological examination 7600 women were divided into two groups. The TCT was applied to the observation group（3800 cases）. The Pap smear was applied to the control group （3800 cases）. Results The positive rate of cervical intraepithelial neoplasia was higher in the observation group （17.26%, 656/3800） than that in the control group （12.24%, 465/3800）（P 〈 0.01 ）. The coincident rate with histopathology was higher in the observation group （96.34%, 632/656） than that in the control group（87.53%,407/465 ）（P 〈 0.05）. But the positive rate of trichomonad was not obviously significant between the two groups（P 〉 0.05 ）. Conclusion The TCT is better than Pap smear, which is worthy of being recommended in diagnosis of cervical disease.