Dementia Neuropsychiatric Symptom Frequency,Severity, and Correlates in Community-Dwelling Thai Older Adults |
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| Institution: | 1. Department of Psychiatry and Behavioral Sciences (LH), University of California, Davis, Sacramento, CA;2. Graduate School of Social Work (KW), University of Denver, Denver, CO;3. College of Social Work (SL), University of South Carolina, Columbia, SC;4. Society and Health Foundation and Sirindhorn Anthropology Center (KC), Bangkok, Thailand;5. Boromarajonani College of Nursing (SS), Khon Kaen, Thailand;6. Chumphae Hospital (TK), Khon Kaen, Thailand;7. Siridhorn Hospital (PI), Khon Kaen, Thailand;8. Department of Psychiatry (SS), Khon Kaen Hospital, Khon Kaen, Thailand;9. Department of Psychiatry and Behavioral Sciences (DGT), Stanford University School of Medicine, Palo Alto, CA;10. Department of Psychiatry (HC), Harvard Medical School, Boston, MA;1. Weill Cornell Medicine (DS), Department of Medicine, Division of Geriatrics and Palliative Care, New York, NY;2. Weill Cornell Medicine (DS), Department of Psychiatry, New York, NY;3. Columbia University (SC, JL, HP), Department of Psychiatry, New York, NY;4. New York State Psychiatric Institute (BSR, HP), New York, NY;5. National Hospice and Palliative Care Organization (LB), Alexandria, Virginia;1. Yale School of Medicine, Department of Psychiatry;2. Yale Program in the History of Science and Medicine |
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| Abstract: | BackgroundThailand is experiencing a rapid increase in the number of older people with dementia (PWD). We examined the frequency, severity, and correlates of dementia neuropsychiatric symptoms (NPS) among community-dwelling Thai older adults.MethodsThis study was based on analysis of baseline data from a larger clinical trial comparing two different implementation approaches of an evidence-based exercise intervention for people with dementia. To be eligible, participants needed to be age 60 and above, have probable dementia, have one or more NPS, be ambulatory, and have an adult (age 18+) family caregiver. In the 353 eligible participants, we examined the correlation between NPS severity and caregiver distress (assessed by the Neuropsychiatric Inventory Questionnaire or NPI-Q) and used ordinary least squares (OLS) regression to examine associations between PWD and caregiver characteristics and NPS severity.ResultsNPS frequency varied from 18% for appetite and/or eating changes to 42% for delusions. NPS severity was significantly (p <0.05) associated with caregiver stress for all individual NPS. Among PWD characteristics, higher ADL score (less functional impairment) was inversely associated with NPS total severity (b = -0.16, p <0.05). More physical role limitation was significantly associated with higher NPS total severity (b = 0.77, p <0.001). Among caregivers’ characteristics, higher burden was significantly associated with higher NPS total severity (b = 0.19, p <0.001).ConclusionOur study found NPS to be common among community-dwelling PWD in Thailand and have adverse impacts on both PWD and family caregivers. These findings highlight the clinical importance of NPS symptoms among Thai older adults. |
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