The potential of iodinated contrast reduction in dual-energy CT thoracic angiography; an evaluation of image quality |
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Affiliation: | 1. Department of Radiology and Nuclear Medicine, Oslo University Hospital, Norway;2. Faculty of Health Science, Oslo Metropolitan University, Norway;3. Sunnaas Rehabilitation Hospital, Norway;4. ImTECH, Department of Diagnostic Physics, Oslo University Hospital, Norway;1. Interventional Radiology Department, Royal Liverpool University Hospital, Prescot St, L78XP, Liverpool, United Kingdom;2. University of Salford, L613, Allerton Building, M5 4WT, Salford, Manchester, United Kingdom;1. The Christie NHSFT, Manchester, United Kingdom;2. Division of Cancer Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, United Kingdom;1. Department of Radiological Technology, Faculty of Health Science and Technology, Kawasaki University of Medical Welfare, 288 Matsushima, Kurashiki-city, Okayama 701-0193, Japan;2. Department of Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto 860-8556, Japan;3. Department of Medical Physics, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan;4. Department of Cardiovascular Internal Medicine, Tsuchiya General Hospital, Nakajima-cho 3-30, Naka-ku, Hiroshima 730-8655, Japan;5. Department of Diagnostic Radiology, Tsuchiya General Hospital, Nakajima-cho 3-30, Naka-ku, Hiroshima 730-8655, Japan;6. Department of Radiological Technologist, Medical Corporation JR Hiroshima Hospital, Hiroshima, Japan;7. Department of Radiological Technology, Tsuchiya General Hospital, Nakajima-cho 3-30, Naka-ku, Hiroshima 730-8655, Japan;8. Saitama Medical University International Medical Center, 1397-1, Yamane, Hidaka-City, Saitama-Pref, 350-1298, Japan;9. Department of Diagnostic Radiology, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan |
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Abstract: | IntroductionThe purpose of this study was to compare a dual energy CT (DECT) protocol with 50% reduction of iodinated contrast to a single energy CT (SECT) protocol using standard contrast dose in imaging of the thoracic aorta.MethodsDECT with a 50% reduction in iodinated contrast was compared with SECT. For DECT, monoenergetic images at 50, 55, 60, 65, 68, 70, and 74 keV were reconstructed with adaptive statistical iterative reconstruction (ASiR-V) of 50% and 80%. Objective image quality parameters included intravascular attenuation (HU), image noise (SD), contrast-to-noise ratio (CNR), and signal-to-noise ratio (SNR). Two independent radiologists subjectively assessed the image quality for the 55 and 68 keV DECT reconstructions and SECT on a five-point Likert scale.ResultsAcross 14 patients, the intravascular attenuation at 50–55 keV was comparable to SECT (p > 0.05). The CNRs were significantly lower for DECT with ASIR-V 50% compared to SECT for all keV-values (p < 0.05 for all). For ASIR-V 80%, CNR was comparable to SECT at energies below 60 keV (p > 0.05). The subjective image quality was comparable between DECT and SECT independent of keV level.ConclusionThis study indicates that a 50% reduction in iodinated contrast may result in adequate image quality using DECT with monoenergetic reconstructions at lower energy levels for the imaging of the thoracic aorta. The best image quality was obtained for ASiR-V 80% image reconstructions at 55 keV.Implications of practiceDual energy CT with a reduction in iodinated contrast may result in adequate image quality in imaging of the thoracic aorta. However, increased radiation dose may limit the use to patients in which a reduction in fluid and iodinated contrast volume may outweigh this risk. |
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Keywords: | Computer tomography Contrast media Spectral imaging Iodine Monoenergetic images DECT" },{" #name" :" keyword" ," $" :{" id" :" kwrd0040" }," $$" :[{" #name" :" text" ," _" :" dual energy CT SECT" },{" #name" :" keyword" ," $" :{" id" :" kwrd0050" }," $$" :[{" #name" :" text" ," _" :" single energy CT ASiR-V" },{" #name" :" keyword" ," $" :{" id" :" kwrd0060" }," $$" :[{" #name" :" text" ," _" :" Adaptive statistical iterative reconstruction Veo CTA" },{" #name" :" keyword" ," $" :{" id" :" kwrd0070" }," $$" :[{" #name" :" text" ," _" :" Computed Tomography Angiography |
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