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Primary germinal center-resident T follicular helper cells are a physiologically distinct subset of CXCR5hiPD-1hi T follicular helper cells
Affiliation:1. Department of Immunology, Duke University School of Medicine, Durham, NC 27710, USA;2. Laboratory for Tissue Dynamics, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa 230-0045, Japan;3. Graduate School of Medical Life Science, Yokohama City University, Yokohama, Kanagawa 230-0045, Japan;4. Laboratory of Lymphocyte Differentiation, WPI Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan;5. Laboratory for Lymphocyte Differentiation, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa 230-0045, Japan;6. Department of Surgery and Duke University Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA
Abstract:
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  • Keywords:germinal centers  Tfh cells  humoral immunity  T:B interaction  S1pr2  affinity maturation
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