Blocking TLR2 activity diminishes and stabilizes advanced atherosclerotic lesions in apolipoprotein E-deficient mice |
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Authors: | Xiao-xing Wang Xiao-xi Lv Jia-ping Wang Hui-min Yan Zi-yan Wang Han-zhi Liu Xiao-ming Fu Zhuo-wei Hu |
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Affiliation: | 1.Molecular Immunology and Pharmacology Group, State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Meteria Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China |
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Abstract: | |
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Keywords: | Toll-like receptor 2, cardiovascular disease, atherosclerosis, inflammation, macrophage, ER stress, apoptosis, apolipoprotein E-deficient (ApoE− /− ) mice |
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