Consequences of Preoperative Oral Carbohydrate Consumption in Septal Deviation Patients Undergoing Endoscopic Septoplasty: A Retrospective Cohort Study |
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| Affiliation: | 1. Department of Nursing, Affiliated Kunshan Hospital of Jiangsu University, Suzhou, Jiangsu, China;2. Department of Otolaryngology, Affiliated Kunshan Hospital of Jiangsu University, Suzhou, Jiangsu, China;3. Information Department, Affiliated Kunshan Hospital of Jiangsu University, Suzhou, Jiangsu, China;4. Department of Nutriology, Affiliated Kunshan Hospital of Jiangsu University, Suzhou, Jiangsu, China;1. College of Nursing, University of Kentucky, Lexington, KY;2. Inova System Nursing Professional Development, Inova, Falls Church, VA;3. Department of Nursing Practice, Clinical and Patient Education, MHealth Fairview Minneapolis, Minneapolis, MN;4. Department of Anesthesia/Acute Pain Management, Baptist Health Lexington, Lexington, KY;1. Department of Anesthesiology & Perioperative Medicine, Penn State Health Milton S. Hershey Medical Center & Children''s Hospital, Hershey, PA;2. Department of Public Health Sciences, Penn State College of Medicine, Hershey, PA;1. Mercy Medical Center, Owings Mills, Baltimore, MD;2. Vanderbilt University Medical Center, Nashville, TN;3. Johns Hopkins Hospital, Baltimore, MD;4. Stony Brook University Hospita, Stony Brook, NY;5. Evansville Surgery Center, Evansville, Indiana;1. Department of Anesthesiology, University Hospital of Larissa, Mezourlo, Larissa, Greece;2. Department of Surgery, University Hospital of Larissa, Mezourlo, Larissa, Greece |
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| Abstract: | PurposeMultiple reports have demonstrated the benefits of preoperative oral carbohydrates (CHO) in patients receiving open abdominal, thoracic, and orthopedic surgeries. However, thus far, no reports have investigated the benefits of CHO in patients undergoing nasal endoscopic surgery. Our goal was to evaluate the outcome of preoperative oral of administration of CHO in septal deviation patients, undergoing endoscopic septoplasty, under general anesthesia.DesignA retrospective cohort study from a prospectively collected database.MethodsConsecutive 400 septal deviation patients, undergoing endoscopic septoplasty, were randomly assigned to receive CHO or plain water (80 CHO cohort vs. 320 control cohort) before general anesthesia. The primary outcome was the risk of acute postoperative hypertension (APH). The secondary outcomes included length of hospital stay (LOS), hospitalization cost, sleep time the day before surgery, fluid infusion volume on surgical day, as well the incidence of postoperative nausea and vomiting (PONV) and aspiration.FindingsPatients in the CHO cohort experienced a lower risk of both diastolic blood pressure (DBP)-based APH (OR, 0.49; 95% CI, 0.25 to 0.96; P = 0.0375) and total APH (OR, 0.49; 95% CI, 0.26 to 0.92; P = 0.0258), lower LOS, lower hospitalization cost, longer sleep time and less fluid infusion volume after adjusting for gender, age, BMI, preoperative blood pressure and pulse. Besides, data showed no significant differences in the incidence of (P = 0.4173) and aspiration (P > 0.99).ConclusionsPreoperative CHO administration can reduce APH risk in patients undergoing endoscopic septoplasty under general anesthesia. Besides, preoperative CHO administration can improve other clinical outcomes, such as, LOS, hospitalization cost, sleep time, and fluid infusion volume. Moreover, CHO safety was confirmed in our study. In the future, additional investigation is necessary to confirm our results. |
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