| 双氯芬酸钠缓释微丸胶囊的制备 |
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| 引用本文： | 吴宁苹, 张小平, 焦长宽. 双氯芬酸钠缓释微丸胶囊的制备[J]. 中国现代应用药学, 2001, (4): 290-292. |
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| 作者姓名： | 吴宁苹 张小平 焦长宽 |
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| 作者单位： | 浙江金华康恩贝生物制药有限公司金华 321016 |
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| 摘 要： | 目的：制备膜控释双氯芬酸钠缓释微丸胶囊；方法：以乙基纤维素为包衣材料，以PEG100为致孔剂，经薄膜包衣制备双氯芬酸钠缓释微丸胶囊，并以体外释放度试验来评价；结果：制备的双氯芬酸钠缓释微丸胶囊的体外释药行为符合零级方程，批与批之间的重现性良好；结论：采用该法制备的双氯芬酸钠缓释微丸胶囊缓释效果好，制备工艺稳定。
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| 关 键 词： | 双氯芬酸钠 缓释胶囊 微丸 制备 |
Preparation of Diclofenac Sodium Sustained Release pellet capsules |
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| Wu Ningping, Zhang Xiaoping, Jiao Changkuan. Preparation of Diclofenac Sodium Sustained Release pellet capsules[J]. Chinese Journal of Modern Applied Pharmacy, 2001, (4): 290-292. |
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| Authors: | Wu Ningping Zhang Xiaoping Jiao Changkuan |
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| Abstract: | OBJECTIVE:To prepare Diclofenac Sodium sustained release pellet capsules.METHOD:The capsules were prepared by the selection of coating material with EC as matrix and PEG 1000 as hollow agent,and judged by the release behavior.RESULTS:The results repeated in three batches showed that the release behavior of the pellet capsules followed ZERO equation.CONCLUSION:The capsules had good sustained release effect and the process of the preparation was steady. |
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| Keywords: | Diclofenac Sodium Sustained release capsules pellet Preparation |
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