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应用固相抗HBs双抗体ELISA技术检测慢性HB患者血清中HBsAg特异性免疫复合物
引用本文:温蒞,韩钦,曹祖华,陈仁.应用固相抗HBs双抗体ELISA技术检测慢性HB患者血清中HBsAg特异性免疫复合物[J].首都医学院学报,1985,6(2):95-100.
作者姓名:温蒞  韩钦  曹祖华  陈仁
作者单位:北京第二医学院微生物学教研室,北京第二医学院微生物学教研室,北京第二医学院微生物学教研室,北京第二医学院微生物学教研室
摘    要:介绍一种应用固相抗HBs-BLISA技术分类检测IgG和IgM类抗体形成的HBsAg特异性CIC的方法。本方法最适检出抗原稍过量的HBsAg-CIC。对不同类型慢性HB患者检测的结果表明,HBAC、CAH较CPH的HBsAg-CIC检出率高,且IgM类抗体形成的HBsAg—CIC与病型区别和活动性肝损害的关系更为密切。


The Detection of HBsAg--specific CIC in Patients with Chronic HB by Double Antibody ELISA Using Anti--HBs Attached on Solid Phase
Wen Li.The Detection of HBsAg--specific CIC in Patients with Chronic HB by Double Antibody ELISA Using Anti--HBs Attached on Solid Phase[J].Journal of Capital University of Medical Sciences,1985,6(2):95-100.
Authors:Wen Li
Abstract:An assay for the specific detection of HBsAg-CIC composed of different immunoglobulins (IgG and IgM) by ELISA using anti-HBs attached on solid phase was reported in this paper. thismethod was most suitable for the detection of HBsAg-CIC with slightly exce-ssive antigen. The results of the detection in different types of patients with chronic HB showed that the incidence of HBsAg-CIC in HBAC and CAH was remarkably higher than that in CPH, in ad-dition, BHsAg/IgM was more close-ly related with the difference of disease types and with the activity of liver damage.
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