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Neoadjuvant Therapy for Advanced Rectal Carcinoma in China: Whether Radiochemotherapy Is Superior to Radiotherapy?
作者单位:[1]Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education)Department of Radiotherapy, Beijing Cancer Hospital & Institute, Beijing 100142, China [2]Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education); Department of Colorectal Surgery, Peking University School of Oncology, Beijing Cancer Hospital & Institute, Beijing 100142, China
摘    要:

关 键 词:放射治疗  辅助治疗  直肠癌  化疗  晚期  中国

Neoadjuvant therapy for advanced rectal carcinoma in China: Whether radiochemotherapy is superior to radiotherapy?
Yong Cai,Chang-zheng Du,Xiang-gao Zhu,Bo Xu,Ming Li,Jin Gu. Neoadjuvant therapy for advanced rectal carcinoma in China: Whether radiochemotherapy is superior to radiotherapy?[J]. Chinese Journal of Cancer Research, 2009, 21(4): 295-303. DOI: 10.1007/s11670-009-0295-1
Authors:Yong Cai  Chang-zheng Du  Xiang-gao Zhu  Bo Xu  Ming Li  Jin Gu
Affiliation:(1) Roswell Park Cancer Institute and the University of Buffalo, State University of New York, Buffalo, NY, USA;(2) Department of Surgery, University of Minnesota, St. Paul, MN, USA;
Abstract:

Objective  

To verify whether the 30 Gy preoperative radiotherapy regimen is effective to advanced rectal cancer, and whether the preoperative chemoradiation offers an advantage in sphincter preservation and tumor control compared with irradiation alone.
Keywords:Rectal carcinoma  Neoadjuvant radiotherapy  Total mesorectal excision  Tumor downstaging  Pathologic complete response
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