院内感染耐甲氧西林金黄色葡萄球菌的监测及耐药分析

目的了解医院内耐甲氧西林金黄色葡萄球菌（MRSA）的感染现状和耐药情况，为有效防治医院内MRSA感染提供依据。方法对武汉大学人民医院住院病人分离的183株金黄色葡萄球菌（SA）用头孢西丁纸片法鉴定分离MRSA阳性菌株，并对MRSA感染患者的科室分布和体外抗菌活性进行分析。结果MRSA感染主要是以神经外科和呼吸内科病房为主；MRSA对青霉素G100．0％耐药，对环丙沙星、克林霉素、红霉素、庆大霉素耐药率大于80％。结论对高危病房进行监控，指导临床合理使用抗生素，有利于控制医院MRSA感染。

Surveillance and Resistance Analysis on Methicillin-resistant Staphylococcus Aureus Involved in Nosocomial Infection

[Objective]To understand the nosocomial infection of metcillin-resistant Staphylococcus aureus(MRSA)and its drug resistance,and provide evidence for effective control of it.[Methods]Cefoxitin disk diffusion method was adopted to isolate MRSA-positive strains from 183 strains of Staphylococcus aureus which was isolated from impatiens in Wuhan University Affiliated People's Hospital.The distribution and in vitro antibacterial activity of MRSA were analyzed.[Results]MRSA infection occurred mainly in Department...