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糖尿病患者血小板维生素E的研究
引用本文:陈蔚,伍汉文,超楚生,廖二元,唐爱国.糖尿病患者血小板维生素E的研究[J].中南大学学报(医学版),1995(2).
作者姓名:陈蔚  伍汉文  超楚生  廖二元  唐爱国
作者单位:Chen Wei(Department of Medicine,The Third Affiliated Hospital,Hunan Medical University )Wu Hanwen; Chao Zusheng(Department of Medicine,The Second Affiliated Hospitl,Hunan Medical University)
摘    要:应用荧光法测定非胰岛素依赖型糖尿病(NIDDM)患者及正常人血小板VitE水平。结果显示:患者的血小板VitE水平明显高于正常对照组;而与空腹血糖、血脂、糖化血红蛋白、过氧化脂质之间无明显相关。正常人50岁以上组的血小板VitE水平与血浆过氧化脂质问呈负相关。结果提示,糖尿病患者存在VitE代谢紊乱,这可能与血管、神经病变有关。

关 键 词:糖尿病  血小板  维生素E  代谢

A STUDY OF VITAMIN E CONCENTRATION IN PLATELETS OF DIABETIC PATIENTS
Chen,Wei.A STUDY OF VITAMIN E CONCENTRATION IN PLATELETS OF DIABETIC PATIENTS[J].Journal of Central South University (Medical Sciences)Journal of Central South University (Medical Sciences),1995(2).
Authors:Chen  Wei
Abstract:itamin E concentration in platelets was estimated in human controls and diabetic pa-tients by fluorometric method.The results showed that:(1) vitamine E concentration inplatelets of NIDDM patients was significantly higher than that of control subjects;(2)therewere no correlation between platelet Vit E content and levels of the FBG,HbAI,lipid perox-ides and serum lipids in NIDDM patients,but in controls,there was negative correlation be-tween platelet Vit E content and plasma lipid peroxides, This suggested that in diabeticsthere is metabolic disturbance of Vit E,which may be associated with vascular complicationsand neuropathy.
Keywords:diabetes mellitus  vitarnin E  blood platelets  metabolism  fluo-rophotomefty
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