新疆地区白癜风患者甲状腺功能的检测

目的检测新疆地区白癜风患者甲状腺功能。方法采用化学发光法对764例白癜风患者进行血清三碘甲状腺原氨酸(T3)、甲状腺素(T4)、游离T3(fT3)、游离T4(fT4)、促甲状腺激素(TSH)、抗甲状腺过氧化酶抗体(TPOAb)、抗甲状球蛋白抗体(TGAb)检测,并将结果与参考区间比较。结果 505例女性患者中,T3升高者51例(10.1%)、T4升高者53例(10.5%)、fT3升高者31例(6.1%)、fT4升高者18例(3.6%)、TSH升高者137例(27.1%),T3降低者38例(7.5%)、T4降低者17例(3.4%)、fT3降低者129例(25.5%)、fT4降低者104例(20.6%)、TSH降低者32例(6.3%),2种自身抗体均升高者78例(15.4%)。259例男性患者中,T3升高者23例(8.9%)、T4升高者19例(7.3%)、fT3升高者11例(4.2%)、fT4升高者5例(1.9%)、TSH升高者29例(11.2%),T3降低者11例(4.2%)、T4降低者9例(3.5%)、fT3降低者63例(24.3%)、fT4降低者31例(12%)、TSH降低者9例(3.5%),2种自身抗体均升高者14例(5.4%)。结论部分白癜风患血清甲状腺功能指标及甲状腺自身抗体水平存在不同程度的异常,且女性异常率高于男性;甲状腺功能异常与白癜风发病有关,女性更为明显。

Thyroid function testing among patients with vitiligo in Xinjiang region

Objective To detect thyroid function in patients with vitiligo in Xinjiang region.Methods Chemiluminescence was applied to measure the serum levels of triiodothyronine（T3）,thyroxine（T4）,free T3（fT3）,free T4（fT4）,thyrotropic-stimulating hormone（TSH）,antithyroperoxidase antibody（TPOAb） and antithyroglobulin antibody（TGAb） in 764 cases of patients with vitiligo,and then compared with reference range.Results Compared with reference range,T3（51 patients,10.1%）,T4（53 patients,10.5%）,fT3（31 patients,6.1%）,fT4（18 patients,3.6%）,TSH（137 patients,27.1%）,TPOAb and TGAb（78 patients,15.4%）were increased in 505 female patients,and T3（23 patients,8.9%）,T4（19 patients,7.3%）,fT3（11 patients,4.3%）,fT4（5 patients,1.9%）,TSH（29 patients,11.2%）,TPOAb and TGAb（14 patients,5.4%）were increased in 259 male patients.Conclusion There could be changes of thyroid function in some vitiligo patients,and more in women than man.The changes of thyroid function might be related with vitiligo,and more apparent in women.