| 食管鳞状细胞癌壁内转移的研究进展 |
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| 引用本文： | 程娜,李卫华,薛丽燕.食管鳞状细胞癌壁内转移的研究进展[J].肿瘤防治研究,2021,48(2):191-195. |
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| 作者姓名： | 程娜 李卫华 薛丽燕 |
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| 作者单位： | 100021 北京，国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院病理科 |
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| 基金项目： | 国家自然科学基金（81972808）；中国医学科学院医学与健康科技创新工程（2016-I2M-3-005） |
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| 摘 要： | 壁内转移是发生在消化道的原发肿瘤通过管壁内的淋巴管网转移至消化道其它部位所形成的与肿瘤原发灶不相连的转移灶,可发生在食管癌、胃癌和结直肠癌中,尤其在食管癌中高发.将组织学形态评估及分子病理手段相结合可辅助鉴别食管癌壁内转移灶及多原发灶.伴有壁内转移的食管鳞癌患者预后更差,同时是否伴有壁内转移影响治疗方式的选择.本文综述...
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| 关 键 词： | 食管癌 壁内转移 多原发灶 临床病理特征 |
| 收稿时间： | 2020-05-09 |
Progress of Intramural Metastasis of Esophageal Squamous Cell Carcinoma |
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| CHENG Na,LI Weihua,XUE Liyan.Progress of Intramural Metastasis of Esophageal Squamous Cell Carcinoma[J].Cancer Research on Prevention and Treatment,2021,48(2):191-195. |
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| Authors: | CHENG Na LI Weihua XUE Liyan |
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| Institution: | Department of Pathology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100021, China |
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| Abstract: | Intramural metastasis (IM) is defined as metastatic tumor from the primary tumor to the digestive tracts through the intramural lymphatic system. It can occur in esophageal, gastric and colorectal carcinomas, especially in esophageal squamous cell carcinoma. The combination of histological morphological evaluation and molecular pathology can assist in the identification of IM and multiple primary carcinomas (MPCs). IM is usually associated with a poor prognosis and also affects the treatment. This article reviews the anatomical and histological basis, clinicopathological characteristics, treatment and prognosis of IM in ESCC, the identification of IM and MPCs and how to improve the detection rate of IM, to guide accurate diagnosis and treatment. |
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| Keywords: | Esophageal squamous cell carcinoma Intramural metastasis Multiple primary carcinomas Clinicopathological characteristics |
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